Examples include nontuberculous mycobacterial infection in GATA2 deficiency42, Staphylococcus aureus and Burkholderia infections in chronic granulomatous disease43, disseminated coccidioidomycosis in STAT3, STAT1, IFN-γR, and IL-12-Rβ deficiency and dysregulation syndromes44, and cryptococcal infection in idiopathic CD4+ lymphopenia45. Here, STAT1 is linked to cryptococcosis.