SMYD3 was expressed at higher levels in multiple HCC cell lines (SK-Hep-1, Huh-7, PLC/PRF/5, Hep3B, SMMC-7721, and HepG2.2.15) than in LO2 cells (Fig. 1F, G and Supplementary Fig. 2). This evidence concerns the gene SMYD3 and hepatocellular carcinoma.