Meanwhile, an increase in the proliferation of CD8+ T cells in the blood within 4 weeks of anti-PD-1 therapy was observed in patients with advanced NSCLC, and it suggested an association with clinical benefit for that therapy.35 Thus, PD-1 blockade may induce the proliferation of CD8+ T cells in responding tumors and cause proliferative pseudoprogression in 18F-FLT PET imaging. Here, CD8A is linked to non-small cell lung carcinoma.