ITGAM and neoplasm: Neutrophils are frequently identified as CD66b+, CD15+CD14−, CD33+ cells in humans and as CD11b+Ly6CintLy6Ghi cells in mice.7 Although tumor-associated neutrophils (TANs) seem to be predominantly associated with bad prognosis and poor response to therapy in multiple solid tumor types,8 they also show some plasticity with important consequences on disease progression.