IGHE and atopic eczema: Additionally, Noti M. et al. found that sensitization to food allergens through an atopic dermatitis-like skin lesion is associated with an expansion of TSLP-elicited basophils in the skin, which promote antigen-specific Th2 cytokine responses, elevated antigen-specific serum IgE levels and the accumulation of mast cells in the intestine, promoting the development of intestinal food allergy [16].