In the present study, we have demonstrated the up-regulation of AQP1, KCNK10, KCNH8, P2RX7, SGK1, SGK2, SLC12A2, SLC6A2, SLC44A1, SLC45A3, SCLC5A11, SCL26A9, CLCA4 and SEPT4 in MAX of FCD type II patients. Here, P2RX7 is linked to isolated focal cortical dysplasia type II.