Network analysis demonstrated associations of CTGF, MAG, TNC, SLC12A2, SLC6A2, SGK1, SPTLC1, NPC1 and TF in MAX vs autopsy and MAP4K4, CNTN2, P2RX7, KCNH8, TNC, GRP, FGF1, TGFA, MAG, PLP1, PLD1, ABCA2, ABCA8, AQP1, ATF3, ELOVL1, MOG and NPC in MAX vs MIN, further strengthen their role in pathophysiology of FCD type II (Fig. 5). Here, PLP1 is linked to isolated focal cortical dysplasia type II.