Comparing HIV women with treatment failure and those without, we observed that shorter duration of cumulative undetectable HIV VL, or VL  >  50 copies/ml at the time of HSIL treatment, higher maximum VL between time of HIV diagnosis and cervical excision, a lower CD4/CD8 ratio, lower nadir CD4 count and lower CD4 count at time of dysplasia were associated with higher rates of treatment failure. This evidence concerns the gene CD4 and dysplasia.