For example rates of ≥ grade 3 infection, thrombocytopenia, or, any grade of vomiting or diarrhoea are similar to data from Phase 2 studies of other HDAC inhibitors (vorinostat, romidepsin, belinostat, panobinostat): grade ≥ 3 infection 3–18%, grade ≥ 3 thrombocytopenia 2–26%, grade ≥ 3 anaemia 2–18%, any grade of vomiting 24–39% and any grade of diarrhoea 20–49% [7–9, 13, 25]. This evidence concerns the gene HDAC9 and infection.