On days when PTH subjects had headache, subjects had significantly longer pause rates (p = 0.0043), slower sentence speaking rates (not normalized: p = 0.0369; normalized: p = 0.0137) and less precise vowel (not normalized: p = 0.049; normalized vowel articulation was not significant: p = 0.1948) and consonant articulation (not normalized: p = 0.0028; normalized: p = 0.0038) compared to healthy controls. The gene discussed is PTH; the disease is Headache.