A growing interest in the use of AMH to predict reproductive health outcomes related to response to controlled ovarian stimulation [23], diagnosis of ovulatory disorders [24], the onset of menopause [25], and even natural conception [26] necessitate an understanding of biological factors, such as obesity, that could impact the predictive power of AMH for such reproductive outcomes. Here, AMH is linked to obesity due to melanocortin 4 receptor deficiency.