Moreover, a relationship has been demonstrated between the concentration of IL-22 and the degrees of histological differentiation of cancer, including: G2 and G3, and between G1 and G3 in the serum of women, which indicates the relationship of this cytokine with tumor development and may in the future prove useful in selecting the optimal therapeutic treatment and in assessing the prognosis. The gene discussed is IL22; the disease is neoplasm.