TNF and metabolic syndrome: Dietary supplementation of anthocyanins (320 mg/daily) was also associated with inhibiting the expression of pro-inflammatory genes and factors related to NF-κB pathways including TNF-α (by −28% and −15%), IL-6 (−16.1% and −13.6%), IL-1A (−21.5% and −12.9%), platelet endothelial cell adhesion molecule-1 (PCAM-1) (−15% and −17.5%), and COX-2(−26% and −27%) in both MetS and control group, respectively [89].