We incubated LFs derived from CLAD and CTD-ILD patients (CD44-positive cells) and 16HBE (CD44-negative cells) with fluorescent PEG-LIP and PEG-LIP-HA400kDa for 4 h at 37 °C analyzing liposomes internalization by flow cytometry and confocal microscopy. Here, CD44 is linked to interstitial lung disease.