OXT and obesity due to melanocortin 4 receptor deficiency: In a more recent investigation looking at a cohort of 109 men and women with a wide range of BMIs and without diabetes, oxytocin levels were similar in all BMI categories (healthy weight, overweight, class I and II obesity), with the exception of individuals with BMI > 40 kg/m2 who had significantly elevated oxytocin levels [203].