Leti et al. demonstrated the over-expression of three lncRNA (i.e., nuclear paraspeckle assembly transcript 1, NEAT1; hepatocellular carcinoma upregulated lncRNA, HULC; MALAT1) in patients with advanced liver fibrosis compared to NAFLD patients with steatosis and/or lobular inflammation [114]. The gene discussed is MALAT1; the disease is metabolic dysfunction-associated steatotic liver disease.