CENPS and cancer: Secondly, the data show DEG shifts that are unique to paclitaxel, which is reportedly observed to be associated with taxol chemoresistance, such as upregulated transcription of kinesin superfamily members, spindle assembly processes (e.g., MAD2, KIF11 (also known as kinesin-5 and Eg5), centrosomal proteins, centromere proteins, cell-division-cycle-associated genes, cyclins, centrioles, and aurora A, some of which also amplify chromosomal and spindle processes in paclitaxel refractory cancers [49,50,51,52] (see Supplementary Table S1).