STAT1 and neoplasm: Given that the CD11b+Ly6ClowLy6G+ cell populations were significantly increased in the spleens and blood of tumor-bearing STAT1-/- mice at the very early stages of tumor transformation (Day 20, Figure 2), as well as the accumulation of neutrophils in the intestine (Figure 1F,G), we decided to perform an intraperitoneal injection of anti-IL-17 neutralizing antibody during the first DSS cycle (Figure 3A) and analyze the course of the disease for 77 days.