STAT1 and neoplasm: In our study, following CAC induction, STAT1-deficient mice developed accumulations of CD11b+Ly6ClowLy6G+ granulocytic cells in their spleens and mature neutrophils in the intestine, accompanied by the accelerated appearance of inflammation and tumor formation, advanced dysplasia, elevated colonic epithelial cell proliferation, and reduced apoptosis in the colon.