A genome-wide association study indicated that four single-nucleotide polymorphisms in CRACR2A/Rab46 (EFCAB4B) caused periodontal diseases [59], and nonalcoholic fatty liver (NAFL) and/or nonalcoholic liver disease (NAFLD) [60,61,62,63]. The gene discussed is CRACR2A; the disease is non-alcoholic fatty liver.