NFKB1 and neoplasm: In addition, it has been reported that curcumin has robust potency as an anti-inflammatory, anti-cytokine, anti-bacterial, anti-viral, anti-tumor, cardioprotective agent, and can also suppress cytokine production by specifically suppressing the NF-kB phosphorylation, which is why it is referred to as a natural NF-kB inhibitor [18,19,20,21].