Stimulator of IFN genes (STING) is an endoplasmic-reticulum (ER)-membrane downstream adaptor protein of an intracellular DNA sensor, which can bind and activate TBK1 kinase and then induce the phosphorylation of several transcription factors, such as IRF3, and type I IFNs production, playing a crucial role in anti-virus and anti-tumor responses [24,25,26]. The gene discussed is STING1; the disease is neoplasm.