IL4 and infection: As expected, the expression of GATA-3 and T-bet was increased in T cells cultured with IL-2-IL-4 and IL-2-IL-12p70 (Figure 4A), and IL-2-IL-12-cultured T cells, but not IL-2-IL-4-cultured T cells, significantly inhibited Mtb growth in macrophages compared to the infection control (Figure 4B).