Several studies showed a differential expression of various proteins such as haptoglobin, kininogen 1, transferrin, serum amyloid A protein, plasma kallikrein, integrin alpha-11, apolipoprotein A-I, sulfhydryl oxidase 1 and isoform-1 of multimerin-1 in the sera of MM patients [128,129,130]. This evidence concerns the gene KLK4 and Miyoshi myopathy.