Several RBPs identified in our study (HNRNPK, PCBP2, PCBP1, NONO, HNRNPH2, RBMX, and RBM8A) have already been shown to have an active role in HCC [35,36,37,38,39,40,41,42,43,44]. This evidence concerns the gene HNRNPK and hepatocellular carcinoma.