Furthermore, analysis of blood samples from pediatric MS patients detected six common proteins (across different MS phenotypes; Table 4)—alpha-1-acid glycoprotein, alpha-1B glycoprotein, apolipoprotein, clusterin, gelsolin, and vitamin D binding protein [79]—suggesting that some alterations of key proteins occur early in life and are subsequently sustained. This evidence concerns the gene CLU and myeloid sarcoma.