Compared with normal tissues, the S11 locus of RCC1 showed higher phosphorylation levels in breast cancer (p < 0.001), colon cancer (p < 0.001), clear cell RCC (p < 0.001) and LUAD (p < 0.001), but not significantly in ovarian cancer (p = 0.09) and UCEC (p = 0.37) (Figure 5b). Here, RCC1 is linked to malignant colon neoplasm.