It was found that in ACC, GBM, LUSC, UCEC, LIHC, SARC, COAD, STAD and UCS, the expression of RCC1 was all positively correlated with MSI (Figure 8a, all p < 0.05) and the expression of RCC1 in ACC, LUAD, PRAD, UCEC, COAD, STAD, SKCM, KIRC, READ, KICH and UCS was positively correlated with TMB (Figure 8b, all p < 0.05). This evidence concerns the gene RCC1 and adrenal cortex carcinoma.