The therapeutic potential of monoterpenes and monoterpenoids in the treatment of AD is based on: (1) inhibition of Aβ-induced neurotoxicity; (2) decreased tau-protein phosphorylation, thereby NFTs formation; (3) promotion of Aβ clearance; (4) attenuation of oxidative stress by boosting antioxidant defenses; (5) reduction of neuroinflammation; (6) restoration of mitochondrial function; (7) initiation of processes with simultaneous inhibition of pro-apoptotic genes and proteins, as well as AChE inhibition. The gene discussed is MAPT; the disease is Alzheimer disease.