Noteworthy, several histone methylation modifiers have been related to miRNA regulation, such as EZH2 in ovarian cancer, which has been shown to induce the repressive histone mark H3K27me3 in target miRNAs: miR-101-3p, let-7e-5p, miR-26a-5p, miR-98-5p, and miR-141-3p [43]. This evidence concerns the gene EZH2 and ovarian cancer.