RUNX1 (Runt-related TF 1, also known as the AML protein 1 and the core binding factor subunit alpha-2, CBFA2) interacts with the LSD1–CoREST–HDAC1/2 complex which, together with GFI1B (growth factor independent 1B transcriptional repressor), suppresses myeloid differentiation in HEL (erythroleukemia) and MEL (lymphoma) cells [62]. The gene discussed is RUNX1; the disease is lymphoma.