The GT1-7 cells, which were developed by genetical targeted tumorigenesis of mouse hypothalamic neurons, possess neuronal characteristics, such as the extension of neuritis, secretion of gonadotropin-releasing hormone (GnRH), and expression of neuron-specific proteins or receptors, including microtubule-associated protein 2 (MAP2), tau protein, neurofilaments, synaptophysin, GABA receptors, dopamine receptors, and L-type Ca2+ channels [42]. Here, MAP2 is linked to neuritis.