In the hepatobiliary phase of EOB-MRI, HCC typically shows low intensity, while HCC with the WNT/β-catenin mutation shows iso-high intensity because WNT/β-catenin mutations result in higher organic anion transporter 1B3 (OATP1B3) expression than in surrounding non-HCC hepatocytes [9,10,11]. This evidence concerns the gene SLCO1B3 and hepatocellular carcinoma.