This is also supported by the fact that exogenously modified human GAL-9 exhibited a proapoptotic effect on five different derived cell lines of chronic myelogenous leukemia [73], while endogenous GAL-9 was shown to drive the self-renewal capacity of AML blasts [31]. The gene discussed is LGALS9; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.