As might be expected for EGFR internalization and accumulation in recycling endosomes, D-Prop reduced the invasive migration of EIH1299-R273H, G-415-R282W and Panc-1-R273H tumor cells that were tested in fibronectin-enriched Matrigel using complete cell culture media supplemented with EGF as chemo-attractant (Figure 2B,C). This evidence concerns the gene EGF and neoplasm.