In addition, expression of stress response-associated proteins, such as superoxide dismutase 2 (SOD2), epoxide hydrolase 1 (EPHX1), peroxiredoxin 1 (PRDX1) and 4 (PRDX4), Tu translation elongation factor (TUFM), DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A (DDX39A) and famous HCC marker, alpha-fetoprotein (AFP), was decreased. Here, SOD2 is linked to hepatocellular carcinoma.