When the various classifiers implemented in PABLO were simply applied to predict available pathological or genetic characteristics related to glioma, such as GBM/LrGG classification (GBM prediction) and IDH mutation prediction (IDH prediction), the AUROC of the method was 0.904 for GBM prediction and 0.867 for IDH prediction; scores were comparable to those of previous methods, including a study based on DL [13,45]. The gene discussed is IDH1; the disease is glioma.