VEGFA and neoplasm: Known to be involved in multiple angiogenic processes including endothelial cell survival, proliferation, migration, and hyperpermeability, VEGF-A is also known to have nonangiogenic tumor-promoting effects including suppression of the antitumor immune response by inhibiting the maturation of dendritic cells, inhibition of tumor cell apoptosis, the stimulation of metastasis, and increasing the permeability of tumor blood vessels, which reduces the delivery of chemotherapeutic agents to the tumor [10,11].