BRCA1 and cancer: This study included 80 cases with no prior BRCA1/2 testing and 443 cases negative for BRCA1/2. Eighty-seven (16.7%) had first-degree FH of BC/OC and 230 (44.1%) of any cancer. PH of other cancers, mostly prostate, colorectal, and bladder cancer, was observed in 99 cases (18.9%).