We previously demonstrated that the combination of a MET-targeting antibody (MvDN30) with an HGF-sequestering protein (DecoyMETK842E) strongly inhibits the HGF/MET axis in HPAF-II cells, resulting in a dramatic reduction in the ability of pancreatic cancer cells to metastasize to the lungs [19,20]. This evidence concerns the gene HGF and familial pancreatic carcinoma.