To investigate the effect of MET pathway stimulation on tumor-stroma activation, we evaluated α-smooth-muscle actin (α-SMA) expression by human pancreatic stellate cells (PSCs) co-cultured with human pancreatic adenocarcinoma cells (Capan-1 or HPAF-II) and treated with the combination of MvDN30 and DecoyMETK842E (Combo). Here, MET is linked to neoplasm.