TNBC tumours showed overexpression of VEGF-A, NOTCH1, CXCR4, IL8, SFRP1, and HIF1α. Significant correlations were observed between FMISO uptake and VEGF-A (ρ = 0.475, p < 0.001), HIF1α (ρ = 0.347, p = 0.007), and IL-8 (ρ = 0.363, p = 0.004) expression. Here, CXCR4 is linked to neoplasm.