COMP and Cirrhosis: Of note, the combined positivity for GP73 and COMP were associated with the presence of cirrhosis at baseline; 23/24 (95.8%) for GP73(+)/COMP(+) vs. 22/30 (73.3%) for GP73(+)/COMP(−) vs. 25/37 (67.6%) for GP73(−)/COMP(+) vs. 46/197 (23.4%) for GP73(−)/COMP(−) (P < 0.001).