PCGEM1 and Familial prostate cancer: GLUT-1 over-expression and consequent glucose influx, for example, are regulated by miR-130b, miR-19a/b and miR-301a in renal clear cell tumors, and by the lncRNA PCGEM1 in prostate cancer (Figure 2), where the expression of the gene is also associated with invasiveness and matrix metalloproteinase-2 (MMP-2) activity [31].