The CEBP family, including CEBPα and CEBPβ, gained high scores due to their significant downregulation upon RANBP2 overexpression (Figure 2A), similar to previous reports on the HCC-suppressive function of CEBPα [21], in contrast to the promoting role of CEBPβ [22]. The gene discussed is CEBPB; the disease is hepatocellular carcinoma.