These genes in this set regulated both by EV numbers and tumor CCL5 expression are altered in a variety of solid tumor types, including melanoma, lung, bladder, ovarian, stomach, head and neck, uterine, breast, cervical, colorectal, liver, and prostate cancer as well as high- and low-grade gliomas (Figure 7A). The gene discussed is CCL5; the disease is Familial prostate cancer.