A recent study conducted on wide type (Wt) and forced growth hormone (GH) expressing MDA-MB-453 and MDA-MB-231 cells has demonstrated that curcumin exposure not only reduced the cell viability and exerted its anti-invasive and metastatic effect, but also caused a dose-dependent reduction in GH expression in GH-expressing breast cancer cells. This evidence concerns the gene GH1 and breast carcinoma.