In MEC1 (CLL), nuclear prohibitin and HSP70C demonstrated increased levels, while nuclear ribonucleoproteins snRNP F, hnRNP H3 and hnRNP K, proliferating cell nuclear antigen (PCNA) and heterogeneous nuclear ribonucleoprotein D0 (AUF1) demonstrated decreased levels, compared to HL-60 (AML), CCRF-CEM (T-ALL), and Raji (BL). The gene discussed is HNRNPK; the disease is B-cell chronic lymphocytic leukemia.