Similarly, in the hyperuricaemia mouse model, the expression of HOTAIR, as determined by qPCR, in the kidney tissue of model mice was significantly higher than that in tissue from the healthy control group (Figure 1C), and the serum inflammatory cytokines IL‐1β and IL‐18 were also significantly higher in the model mice than in the control group (Figure 1D). This evidence concerns the gene IL18 and hyperuricemia.