CXCL8 and cystic fibrosis: A significant decrease in neutrophil, eosinophil, and macrophage amounts, as well as reduction of various molecules, namely neutrophil elastase, interleukin-8 (IL-8), interleukin-6, and tumor necrosis factor-α, was observed in nasal secretions obtained from CF patients with CRS undergoing clarithromycin and roxithromycin therapy [35].