The expression of typical integrins is mainly α4β1 (integrin very late antigen-4, VLA-4) and α5β1 (VLA-5) in hematologic malignancies, especially VLA-4 is highly expressed in multiple myeloma (MM) cells and most normal B lymphocytes (Mraz et al., 2011). Here, ITGA5 is linked to hematologic disorder.