FOXO1 and cancer: These results not only are in line with other studies that reported inhibitory effect of FoxO1 on metastasis and EMT in malignancies (Kojima et al., 2010; Yang et al., 2014; Ko et al., 2015; Du et al., 2016; Dong et al., 2017; Gao et al., 2018), but also demonstrate another mechanism underlying oncogenic properties of STYK1.