However, considering that high STYK1 expression correlates with an advanced stage and lower 5-year survival rate in our study and STYK1 being one of the prognostic factors in other malignancies, we believe STYK1 might still be an independent prognostic factor in NSCLC, and further studies would be needed to verify this. This evidence concerns the gene STYK1 and non-small cell lung carcinoma.