Currently, there is no evidence regarding whether the p.P479L variant impairs immune response and/or memory T cell response to repeat infection in humans; however, a recent study of a multiple sclerosis (MS) mouse model (autoimmune encephalomyelitis) found that the CPT1A p.P479L variant may affect the function of cells important in immunity (35). The gene discussed is CPT1A; the disease is multiple sclerosis.