We conducted gene ontology terms analysis of NEK6 in normal tissues and tumor tissues, the results showed that a proportion of differentially expressed genes was associated with focal adhesion, cell substrate adherens junction, cell-substrate junction which was consistent with NEK7, and Ada2/Gcn5/Ada3 transcription activator complex differ from mitochondrial protein complex and mitochondrial inner membrane of NEK7 (Figures S2A, B). Here, ADA2 is linked to neoplasm.